Lilly drug chosen for Alzheimer's prevention study

Researchers have chosen an experimental drug by Eli Lilly & Co. for a large federally funded study testing whether it's possible to prevent Alzheimer's disease in older people at high risk of developing it.

The drug, called solanezumab (sol-ah-NAYZ-uh-mab), is designed to bind to and help clear the sticky deposits that clog patients' brains.

Earlier studies found it did not help people with moderate to severe Alzheimer's but it showed some promise against milder disease. Researchers think it might work better if given before symptoms start.

"The hope is we can catch people before they decline," which can come 10 years or more after plaques first show up in the brain, said Dr. Reisa Sperling, director of the Alzheimer's center at Brigham and Women's Hospital in Boston.

She will help lead the new study, which will involve 1,000 people ages 70 to 85 whose brain scans show plaque buildup but who do not yet have any symptoms of dementia. They will get monthly infusions of solanezumab or a dummy drug for three years. The main goal will be slowing the rate of cognitive decline. The study will be done at 50 sites in the U.S. and possibly more in Canada, Australia and Europe, Sperling said.

In October, researchers said combined results from two studies of solanezumab suggested it might modestly slow mental decline, especially in patients with mild disease. Taken separately, the studies missed their main goals of significantly slowing the mind-robbing disease or improving activities of daily living.

Those results were not considered good enough to win the drug approval. So in December, Lilly said it would start another large study of it this year to try to confirm the hopeful results seen patients with mild disease. That is separate from the federal study Sperling will head.

About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Current medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.

___

Online:

Alzheimer's info: http://www.alzheimers.gov

Alzheimer's Association: http://www.alz.org

___

Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP

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Wall Street Week Ahead: Earnings, money flows to push stocks higher

NEW YORK (Reuters) - With earnings momentum on the rise, the S&P 500 seems to have few hurdles ahead as it continues to power higher, its all-time high a not-so-distant goal.

The U.S. equity benchmark closed the week at a fresh five-year high on strong housing and labor market data and a string of earnings that beat lowered expectations.

Sector indexes in transportation <.djt>, banks <.bkx> and housing <.hgx> this week hit historic or multiyear highs as well.

Michael Yoshikami, chief executive at Destination Wealth Management in Walnut Creek, California, said the key earnings to watch for next week will come from cyclical companies. United Technologies reports on Wednesday while Honeywell is due to report Friday.

"Those kind of numbers will tell you the trajectory the economy is taking," Yoshikami said.

Major technology companies also report next week, but the bar for the sector has been lowered even further.

Chipmakers like Advanced Micro Devices , which is due Tuesday, are expected to underperform as PC sales shrink. AMD shares fell more than 10 percent Friday after disappointing results from its larger competitor, Intel . Still, a chipmaker sector index <.sox> posted its highest weekly close since last April.

Following a recent underperformance, an upside surprise from Apple on Wednesday could trigger a return to the stock from many investors who had abandoned ship.

Other major companies reporting next week include Google , IBM , Johnson & Johnson and DuPont on Tuesday, Microsoft and 3M on Thursday and Procter & Gamble on Friday.

CASH POURING IN, HOUSING DATA COULD HELP

Perhaps the strongest support for equities will come from the flow of cash from fixed income funds to stocks.

The recent piling into stock funds -- $11.3 billion in the past two weeks, the most since 2000 -- indicates a riskier approach to investing from retail investors looking for yield.

"From a yield perspective, a lot of stocks still yield a great deal of money and so it is very easy to see why money is pouring into the stock market," said Stephen Massocca, managing director at Wedbush Morgan in San Francisco.

"You are just not going to see people put a lot of money to work in a 10-year Treasury that yields 1.8 percent."

Housing stocks <.hgx>, already at a 5-1/2 year high, could get a further bump next week as investors eye data expected to support the market's perception that housing is the sluggish U.S. economy's bright spot.

Home resales are expected to have risen 0.6 percent in December, data is expected to show on Tuesday. Pending home sales contracts, which lead actual sales by a month or two, hit a 2-1/2 year high in November.

The new home sales report on Friday is expected to show a 2.1 percent increase.

The federal debt ceiling negotiations, a nagging worry for investors, seemed to be stuck on the back burner after House Republicans signaled they might support a short-term extension.

Equity markets, which tumbled in 2011 after the last round of talks pushed the United States close to a default, seem not to care much this time around.

The CBOE volatility index <.vix>, a gauge of market anxiety, closed Friday at its lowest since April 2007.

"I think the market is getting somewhat desensitized from political drama given, this seems to be happening over and over," said Destination Wealth Management's Yoshikami.

"It's something to keep in mind, but I don't think it's what you want to base your investing decisions on."

(Reporting by Rodrigo Campos, additional reporting by Chuck Mikolajczak and Caroline Valetkevitch; Editing by Kenneth Barry)

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Priest Is Planning to Defy the Vatican’s Orders to Stay Quiet

Jekaterina Saveljeva for The New York Times

The Rev. Tony Flannery, an Irish priest, was suspended by the Vatican last year. “I refuse to be terrified into submission,” he said.

DUBLIN — A well-known Irish Catholic priest plans to defy Vatican authorities on Sunday by breaking his silence about what he says is a campaign against him by the church over his advocacy of more open discussion on church teachings.

The Rev. Tony Flannery, 66, who was suspended by the Vatican last year, said he was told by the Vatican that he would be allowed to return to ministry only if he agreed to write, sign and publish a statement agreeing, among other things, that women should never be ordained as priests and that he would adhere to church orthodoxy on matters like contraception and homosexuality.

“How can I put my name to such a document when it goes against everything I believe in,” he said in an interview on Wednesday. “If I signed this, it would be a betrayal not only of myself but of my fellow priests and lay Catholics who want change. I refuse to be terrified into submission.”

Father Flannery, a regular contributor to religious publications, said he planned to make his case public at a news conference here on Sunday.

The Vatican’s doctrinal office, the Congregation for the Doctrine of the Faith, wrote to Father Flannery’s religious superior, the Rev. Michael Brehl, last year instructing him to remove Father Flannery from his ministry in County Galway, to ensure he did not publish any more articles in religious or other publications, and to tell him not to give interviews to the news media.

In the letter, the Vatican objected in particular to an article published in 2010 in Reality, an Irish religious magazine. In the article, Father Flannery, a Redemptorist priest, wrote that he no longer believed that “the priesthood as we currently have it in the church originated with Jesus” or that he designated “a special group of his followers as priests.”

Instead, he wrote, “It is more likely that some time after Jesus, a select and privileged group within the community who had abrogated power and authority to themselves, interpreted the occasion of the Last Supper in a manner that suited their own agenda.”

Father Flannery said the Vatican wanted him specifically to recant the statement, and affirm that Christ instituted the church with a permanent hierarchical structure and that bishops are divinely established successors to the apostles.

He believes the church’s treatment of him, which he described as a “Spanish Inquisition-style campaign,” is symptomatic of a definite conservative shift under Pope Benedict XVI.

“I have been writing thought-provoking articles and books for decades without hindrance,” he said. “This campaign is being orchestrated by a secretive body that refuses to meet me. Surely I should at least be allowed to explain my views to my accusers.”

His superior was also told to order Father Flannery to withdraw from his leadership role in the Association of Catholic Priests, a group formed in 2009 to articulate the views of rank-and-file members of the clergy.

In reply to an association statement expressing solidarity with Father Flannery, the Congregation for the Doctrine of the Faith denied it was acting in a secretive manner, pointed out that Father Flannery’s views could be construed as “heresy” under church law, and threatened “canonical penalties,” including excommunication, if he did not change his views.

This month, the Congregation for the Doctrine of the Faith wrote to an American priest, Roy Bourgeois, notifying him of his laicization, following his excommunication in 2008 over his support for the ordination of women.

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100 Years of U.S. Presidential Inaugurations

On March 4, 1913, Woodrow Wilson took the oath of office. Nearly 100 years later, Barack Obama will take that same oath.

The U.S. presidential inauguration looks a tad different than it did a century ago. In 1913, women still did not have the right to vote and Wilson rode to the Capitol in a horse-drawn carriage. And don’t expect to see President Obama wearing a silk top hat like Wilson either.

[More from Mashable: Watch Every President’s Inauguration Since Reagan in 36 Seconds]

Thanks to the digital archiving of government images, zipping through 100 years of presidential history doesn’t even require a trip to the library. We’ve compiled the most memorable photographs and videos taken at presidential inaugurations since 1913 for a scrollable history lesson.

[More from Mashable: The Letters Kids Wrote to Obama About Gun Control]

If you like your history well-aged, then there’s also a special gallery at the bottom featuring images from inaugurations that occurred before 1913 — including those of Abraham Lincoln, Theodore Roosevelt and Ulysses S. Grant.

Woodrow Wilson, March 4, 1913

“President-elect Wilson and President Taft, standing side by side, laughing, at White House prior to Wilson’s inauguration ceremonies” Image courtesy of Library of Congress

Image courtesy of Library of Congress

Image courtesy of Library of Congress

Woodrow Wilson, March 5, 1917

Image courtesy of Library of Congress

“Telegram from Evangeline Booth, Commander of the Salvation Army” Image courtesy of Library of Congress

Warren G. Harding, March 4, 1921

“Woodrow Wilson, Warren G. Harding, Philander Knox and Joseph Cannon, in convertible” Image courtesy of Library of Congress

Image courtesy of Library of Congress

Calvin Coolidge, March 4, 1925

“President Coolidge, Mrs. Coolidge and Senator Curtis on the way to the Capitol” Image courtesy of Library of Congress

Herbert Hoover, March 4, 1929

Image courtesy of Library of Congress

Franklin D. Roosevelt, March 4, 1933

Inaugural Program, Inauguration. Franklin D. Roosevelt President of the United States. John N. Garner Vice President of the United States. Image courtesy of Library of Congress

Image courtesy of Library of Congress

Franklin D. Roosevelt, January 20, 1937

Image courtesy of Library of Congress

Image courtesy of Library of Congress

“Ticket for the 1937 inauguration, the first to take place on January 20th.” Image courtesy of FDR Library

“Eleanor Roosevelt poses in her inaugural gown at the White House.” Image courtesy of FDR Library

Franklin D. Roosevelt, January 20, 1941

“Franklin and Eleanor Roosevelt riding in an open car, returning to the White House from FDR’s third inauguration.” Image courtesy of FDR Library

Excerpt from home movie of FDR driving and walking with assistance to take the Oath of Office on January 20, 1941.

Franklin D. Roosevelt, January 20, 1945

Image courtesy of Library of Congress

“Crowd stands in snow for inauguration” Image courtesy of Library of Congress

Harry S. Truman, January 20, 1949

“Truman and Barkley during Inaugural parade.” Image courtesy of Truman Library

Dwight D. Eisenhower, January 20, 1953

“Ike responds to cheers of crowd.” Image courtesy of Library of Congress

“With smiles and a wave, President Harry Truman and his successor, Dwight D. Eisenhower, leave White House in an open car on way to Capitol for inauguration ceremonies.” Image courtesy of Library of Congress

Dwight D. Eisenhower, January 21, 1957

“President Eisenhower waves to the crowd” Image courtesy of Eisenhower Library

“Dwight Eisenhower and Richard Nixon watching inaugural parade with Anne & David Eisenhower and Julie & Tricia Nixon” Image courtesy of Eisenhower Library

“Dwight and Mamie Eisenhower attend the Inaugural Ball with John and Barbara Eisenhower” Image courtesy of Eisenhower Library

John F. Kennedy, January 20, 1961

Image courtesy of National Archives

“President-elect John F. Kennedy shakes hands with Father Richard J. Casey, the Pastor, after attending Mass at Holy Trinity Church … prior to inauguration ceremonies.” Image courtesy of Library of Congress

Lyndon B. Johnson, January 20, 1965

“President Lyndon B. Johnson, Lady Bird Johnson, Lynda Bird Johnson, and Luci Baines Johnson preparing for Inauguration ceremonies.” Image courtesy of LBJ Library

Image courtesy of Library of Congress

“Secret service agents try to hold back the crowds that surge forward to watch President Johnson dance with the First Lady at the inaugural ball at the National Guard Armory” Image courtesy of Library of Congress

Richard M. Nixon, January 20, 1969

Image courtesy of Library of Congress

“President and Mrs. Nixon waving to the crowd from the Presidential limousine in the inaugural motorcade” Image courtesy of Library of Congress

Richard M. Nixon, January 20, 1973

Image courtesy of White House

Image courtesy of Library of Congress

Jimmy Carter, January 20, 1977

Image courtesy of Jimmy Carter Presidential Library

Image courtesy of Library of Congress

Ronald Reagan, January 20, 1981

Image courtesy of Library of Congress

Image courtesy of Library of Congress

Ronald Reagan, January 21, 1985

Image courtesy of Reagan Library

“1985 Inaugural Ball: President and Mrs. Reagan in National Air and Space Museum” Image courtesy of Smithsonian

George H. W. Bush, January 20, 1989

Image courtesy of Smithsonian

“1989 Presidential Inaugration, George H. W. Bush, Opening Ceremonies, at Lincoln Memorial” Image courtesy of Smithsonian

Bill Clinton, January 20, 1993

“While the Clintons and Gores watch, Chelsea Clinton rings a replica of the Liberty Bell during festivities kicking off the Clinton/Gore 1993 Inaugural events.” Image courtesy of Smithsonian

“George Bush and Bill Clinton shake hands just after the inaugural ceremonies at the U.S. Capitol.” Image courtesy of Smithsonian

Image courtesy of Smithsonian

Bill Clinton, January 20, 1997

Image courtesy of Smithsonian

Image courtesy of Smithsonian

George W. Bush, January 20, 2001

Image courtesy of White House

Image courtesy of Library of Congress

George W. Bush, January 20, 2005

Image courtesy of White House

Image courtesy of White House

Image courtesy of White House

Barack Obama, January 20, 2009

Image courtesy of Master Sgt. Cecilio Ricardo, U.S. Air Force

“President Barack Obama is given the Oath of Office for a second time by Chief Justice John G. Roberts” Image courtesy of Pete Souza/White House

“President Barack Obama and First Lady Michelle Obama share a private moment in a freight elevator at an Inaugural Ball” Image courtesy of Pete Souza/White House

“President Barack Obama and First Lady Michelle Obama ride in a golf cart at an Inaugural Ball” Image courtesy of Pete Souza/White House

BONUS: Pre-1913 Presidential Inaugurations

Inauguration of Abraham Lincoln, March 4, 1861

Image courtesy of Library of Congress

Click here to view this gallery.

This story originally published on Mashable here.

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Marla Sokoloff Blogs: Adventures in Baby Traveling

Shady ladies in Hawaii – Courtesy Marla Sokoloff

Our celebrity blogger Marla Sokoloff is a new mama!

Since audiences first got to know her at age 12 as Gia on Full House, Sokoloff has had many memorable TV roles — Jody on Party of Five, Lucy on The Practice, Claire on Desperate Housewives – as well as turns on the big screen in Whatever It Takes, Dude, Where’s My Car? and Sugar & Spice.

Sokoloff, 32, also sings and plays guitar and released an album, Grateful, in 2005.

She wed her husband, music composer Alec Puro, in November 2009 and the couple — plus pup Coco Puro — make their home in Los Angeles.

You can find Marla, now mom to 11-month-old daughter Elliotte Anne, on Twitter.

Happy 2013! I don’t know about you, but I’m completely amazed at how fast 2012 flew by! I must admit, on New Year’s Day I found myself a little weepy to say goodbye to the year that my little Elliotte came into this world. I realized that as long as I’m on this earth I will always have a soft spot for the year 2012, as it was a complete life and game-changer for me. (Clearly it’s also the year that turned me into a total sap!)

As far as resolutions go, I have a few. They include the usual suspects (exercise more, get more sleep, drink more than four sips of water per day!) but my main focus is going to be on my beloved iPhone and our very dysfunctional relationship.

I really want to work on being in the present and putting that thing down so I can suck up every delicious moment with my family. The social media and pinboards will just have to wait until after my daughter goes to bed. Baby steps!

Last week we hit a huge milestone … Elliotte took her first steps and is now walking (albeit a bit drunk-like) almost on her own! The moment was truly unbelievable and one that left me in tears (shocking … I know) as I was simply overwhelmed with joy. I was just so proud of her.

This is where my resolution isn’t a good thing because — had I not had my trusty iPhone glued to my body — I might have missed the moment. Her grandparents would have killed me! I’m just saying…

Happy New Year! – Courtesy Marla Sokoloff

We spent our Christmas vacation in paradise on the Big Island of Hawaii, but I’m here to tell you that getting there was nothing short of a nightmare. I’m not going to lie or candy-coat this blog at all because this experience was one I never want to relive.

All of my friends warned me about baby airplane travel … basically it could go either way. Kids are wild cards and you never really know what you’re going to get. So in preparation for my little wild card, I boarded our flight armed with earplugs and chocolates for the innocent passengers that could potentially be caught in the line of fire, so to speak. All the while knowing that I will never need to bring out said earplugs … I mean, my child is perfect after all!

This wasn’t Elliotte’s first flight — over the summer we traveled to San Francisco and my little angel slept for the hour flight each way, so I was certain we had this Hawaiian excursion in the bag.

I came equipped with two giant diaper bags. One was filled with diaper bag essentials (diapers, wipes, pacifiers, bottles, change of clothes for both of us) and the other ridiculously large bag was filled with toys and snacks. So many toys and snacks!! If this plane went down, Elliotte could feed the whole cabin with her copious supply of puffs and Cheerios. Basically the plan was, if this kid wasn’t sleeping, I was going to keep her busy and well-fed!

My special edition diaper bag also contained an emergency item. An SOS of sorts. An article that is generally considered a baby no-no in my house, but one that was only to be revealed if absolutely 100 percent necessary. Friends, I’m talking about the iPad. I loaded my secret weapon up with episodes of Sesame Street and adorable farm animal applications that looked like they would keep Elliotte entertained for at least a temper tantrum or two.

Very much like the aforementioned earplugs, I felt pretty confident that our no-no item wouldn’t be making an appearance.

Before takeoff… – Courtesy Marla Sokoloff

As our flight took off, I could see that Elliotte was not the happy camper I know and love. Her face turned beet-red within seconds and she was thrashing in her carseat as if it was a torture device. The tears were flowing fast and her scream was one that could not be silenced.

I looked at my husband, whose eyes said, “Bring out the iPad!!” but I knew it was way too early in our journey to pull such tricks out of sleeves.

As Alec handed out the chocolate and earplugs to our unlucky neighbors, I brought out some of Elliotte’s favorite toys. Every toy that was presented was met with a louder scream. I moved on to my trusted stash of snacks — surely a handful of puffs would soothe this outburst. Fail. I sang. I danced. I peek-a-booed. Nothing.

How can this be? The seat belt sign hasn’t even been turned off yet and I have pretty much emptied out the contents of my special-edition diaper bag!

Once the captain decided to put me out of my misery and turned the seat belt sign off, I ripped Elliotte out of her carseat (the one I brought thinking she would sleep in) and decided a nice walk down the aisle would do us both some good.

That mission was quickly aborted as the scream-fest continued to unaffected rows that were surely enjoying their cocktails and weekly gossip magazines.

My beach baby in Hawaii – Courtesy Marla Sokoloff

I handed her off to my husband and I took a much-needed break, as well as the first deep breath I had taken since leaving Los Angeles International Airport. We were now three-and-a-half hours into our six-hour flight and Elliotte showed no signs of slowing down. It was in this moment that I turned to my family and saw the chaos.

My seat was littered with toys and Cheerios and my poor child looked like a complete mess. Her face was tear-stained and her clothes were covered in squeezable applesauce. (Another failed mission.)

I knew it was time to bring out the big guns. Elmo needed to step in and he better be bringing his A-game.

I placed Elliotte on my lap and out came the iPad. Images of all of my favorite characters appeared on the screen and I instantly felt comforted by my childhood friends. Not only because they are the same characters that were my source of calm as a child, but also I knew they were the lifesavers we so desperately needed.

Well … I guess iPads and big yellow birds aren’t that comforting to teething babies that are 30,000 feet up in the air. The iPad went flying and I sunk into my seat holding my very unhappy girl tight. I was officially out of ideas.

Hawaiian fun in the sun – Courtesy Marla Sokoloff

A kind woman in front of me asked to hold Elliotte. She saw in my eyes that I was breaking down and she was a mom who got it. She understood. She didn’t judge or hate us for disrupting the beginning of her holiday vacation — she was happy to help because she had once been in our shoes with her own child. Elliotte enjoyed the break from her parents and was actually smiling in her arms.

We finally arrived in paradise and upon landing, Alec and I decided that we were moving to Hawaii as we were never going to step foot on a plane ever again.

In all fairness, in between Thanksgiving and Christmas, Elliotte went from having two teeth to eight teeth so I think the plane and cabin pressure exacerbated any existing pain she was already having. Our journey home was slightly better and she even slept for two beautiful hours!

Thank you for letting me share my story — I would absolutely love to hear some of your travel woes! I’m sure it’s even more fun for those of you who have multiple children.

Don’t forget to follow me on Twitter @marlasok or leave your comments below!

Until next time … xo,

– Marla Sokoloff

More from Marla’s PEOPLE.com blog series:

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Wall Street Week Ahead: Earnings, money flows to push stocks higher

NEW YORK (Reuters) - With earnings momentum on the rise, the S&P 500 seems to have few hurdles ahead as it continues to power higher, its all-time high a not-so-distant goal.

The U.S. equity benchmark closed the week at a fresh five-year high on strong housing and labor market data and a string of earnings that beat lowered expectations.

Sector indexes in transportation <.djt>, banks <.bkx> and housing <.hgx> this week hit historic or multiyear highs as well.

Michael Yoshikami, chief executive at Destination Wealth Management in Walnut Creek, California, said the key earnings to watch for next week will come from cyclical companies. United Technologies reports on Wednesday while Honeywell is due to report Friday.

"Those kind of numbers will tell you the trajectory the economy is taking," Yoshikami said.

Major technology companies also report next week, but the bar for the sector has been lowered even further.

Chipmakers like Advanced Micro Devices , which is due Tuesday, are expected to underperform as PC sales shrink. AMD shares fell more than 10 percent Friday after disappointing results from its larger competitor, Intel . Still, a chipmaker sector index <.sox> posted its highest weekly close since last April.

Following a recent underperformance, an upside surprise from Apple on Wednesday could trigger a return to the stock from many investors who had abandoned ship.

Other major companies reporting next week include Google , IBM , Johnson & Johnson and DuPont on Tuesday, Microsoft and 3M on Thursday and Procter & Gamble on Friday.

CASH POURING IN, HOUSING DATA COULD HELP

Perhaps the strongest support for equities will come from the flow of cash from fixed income funds to stocks.

The recent piling into stock funds -- $11.3 billion in the past two weeks, the most since 2000 -- indicates a riskier approach to investing from retail investors looking for yield.

"From a yield perspective, a lot of stocks still yield a great deal of money and so it is very easy to see why money is pouring into the stock market," said Stephen Massocca, managing director at Wedbush Morgan in San Francisco.

"You are just not going to see people put a lot of money to work in a 10-year Treasury that yields 1.8 percent."

Housing stocks <.hgx>, already at a 5-1/2 year high, could get a further bump next week as investors eye data expected to support the market's perception that housing is the sluggish U.S. economy's bright spot.

Home resales are expected to have risen 0.6 percent in December, data is expected to show on Tuesday. Pending home sales contracts, which lead actual sales by a month or two, hit a 2-1/2 year high in November.

The new home sales report on Friday is expected to show a 2.1 percent increase.

The federal debt ceiling negotiations, a nagging worry for investors, seemed to be stuck on the back burner after House Republicans signaled they might support a short-term extension.

Equity markets, which tumbled in 2011 after the last round of talks pushed the United States close to a default, seem not to care much this time around.

The CBOE volatility index <.vix>, a gauge of market anxiety, closed Friday at its lowest since April 2007.

"I think the market is getting somewhat desensitized from political drama given, this seems to be happening over and over," said Destination Wealth Management's Yoshikami.

"It's something to keep in mind, but I don't think it's what you want to base your investing decisions on."

(Reporting by Rodrigo Campos, additional reporting by Chuck Mikolajczak and Caroline Valetkevitch; Editing by Kenneth Barry)

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New Northern Ireland Violence May Be About More Than the British Flag

Peter Muhly/Agence France-Presse — Getty Images

Police officers in Belfast, Northern Ireland, remained with their armored vehicles as a car burned after violence between unionists and loyalists on Jan. 12.

BELFAST, Northern Ireland — For more than six weeks, it has been a dismal case of back-to-the-future, a crudely sectarian upheaval that has defied all attempts at peacemaking.

Paul Faith/Press Association, via Associated Press

Loyalist protests began in Belfast after the City Council voted to reduce the number of days a year the British flag was flown in public, to 18 from 365.

The scenes recall the sectarian bitterness that infused the 30 years of virtual civil war known as the Troubles: night after night of street protests marshaled by balaclava-wearing militants, who have updated their tactics by using social media to rally mobs; death threats to prominent politicians, some of whom have fled their homes and hidden under police guard; firebombs, flagstones and rocks hurled at churches, police cars and lawmakers’ offices; protesters joined by rock-throwing boys of 8 and 9; neighborhoods sealed off for hours by the police or protesters’ barricades.

Many had hoped that the old hatreds between Northern Ireland’s two main groups — the mainly Protestant, pro-British unionists, and the mainly Roman Catholic republicans, with their commitment to a united Ireland — would recede permanently under the auspices of the Good Friday agreement. That accord was reached 15 years ago as a blueprint for the power-sharing government that now rules the province.

But the fragility of those hopes has been powerfully demonstrated by more than 40 days and nights of violence that were triggered by a decision to cut back on the flying of the Union Jack, Britain’s red, white and blue national flag, over the grandly pillared, neo-Classical pile City Council building in central Belfast.

By the latest count, more than 100 police officers have been injured, along with dozens of protesters and bystanders. At times, the violence has expanded to other cities, including Londonderry. Business has slumped. Police commanders, their forces overwhelmed, have assigned dozens of officers to scan hundreds of hours of closed-circuit video, looking for ringleaders.

The crisis began modestly enough. The Belfast council, its pro-British members outvoted by a coalition of republicans and a small liberal bloc, decided in early December to limit the flag flying to 18 days a year, as specified by London for all of Britain. Through the decades when the council was dominated by Protestant unionists, committed to links with Britain, the flag flew from the pinnacle of the building every day of the year.

Incongruously, perhaps, most of those 18 days do not represent landmarks in Britain’s history — Nelson’s victory at Trafalgar, say, or Germany’s surrender in the Second World War — but the birthdays of Queen Elizabeth II and her family members, including the former Kate Middleton, now the Duchess of Cambridge, on whose 31st birthday, Jan. 9, the Belfast flag fluttered for the first time since it came down in early December. Under Britain’s strict rules about flying the national standard on public and private buildings, not even the Parliament buildings in London fly it on any but government-designated days. But the hauling down of the Belfast flag provoked a furious reaction, the most protracted period of unrest in many years in Northern Ireland.

Among pro-British loyalists, the episode was seen as part of the step-by-step erosion of the British presence, a stripping of what many of them call their identity. Other examples they invoke have also been symbolic, including moves to delete the word Ulster — an ancient designation for the northern Irish provinces commonly used by Protestants but mostly shunned by republicans — from the formal names of the province’s police force and its military reservists, and to remove the British crown emblem from the cap and shoulder badges of prison guards and other public officials.

But many of the province’s political commentators see the flag dispute as a token of something more profound and ultimately more threatening to the hopes for a permanent peace here.

They say the council’s decision on the flag, made possible by the fact that nationalists now hold 24 seats on the council, compared with 21 for the unionists, reflects the rapid growth of the Catholic population in the years since the Good Friday agreement, unsettling the long-held assumption among unionists that Protestants would constitute a permanent majority in the province.

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Paid apps are history

This week marked an important moment in the evolution of the iOS app market. As Pages just slipped out of the iPad top 10 highest grossing apps chart, there are now no paid apps among the ten applications that generate most revenue on the iPad. When the iPad application market was born a few years ago, it was dominated by relatively stiffly priced applications, mimicking the PC software or game console software markets. But over the past couple of years, app vendors have realized that free apps with clever in-app purchasing hooks create much more revenue than paid apps.

[More from BGR: BlackBerry 10 browser smokes iOS 6 and Windows Phone 8 in comparison test [video]]

The same applies to the iPhone — there is only one paid app among the twenty highest grossing iPhone apps today. It is notable that some of the highest grossing apps have relatively low download volumes. Clash of Clans has been the top-grossing iPad application for all of January, but it is only ranked 53rd on the iPad download chart. Hay Day is the seventh-biggest application when it comes to revenue generation on the iPhone, but is only ranked at #104 when it comes to download volume.

[More from BGR: Galaxy S IV benchmarks may confirm 1.8GHz CPU and Android 4.2]

Leading app developers have figured out how to decouple download volume from revenue generation by creating free games that seduce their fans into paying steadily for in-app features. The types of of games that require a $ 0.99 or a $ 2.99 fee per download are turning into something resembling nostalgia items. For a stark example of how badly the revenue generation power of paid apps has faded, consider that the current #1 paid app on iPhone, Wood Camera, is 46th on the iPhone chart that lists top-grossing apps.  The future belongs to free apps.

This article was originally published on BGR.com

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Inspiring Singers Outshine American Idol's Feuding Judges

TV Watch

American Idol

By Steve Helling

01/17/2013 at 11:00 PM EST

From left: Randy Jackson, Mariah Carey, Ryan Seacrest, Nicki Minaj and Keith Urban

George Holz/FOX

The second episode of American Idol delivered more drama, but a handful of singers managed to eclipse the ongoing feud between new judges Mariah Carey and Nicki Minaj. And that's no easy task considering one of the battling divas is wearing a blonde and pink wig.

The night's most memorable contestant was Lazaro Arbos. As he entered the audition room, one thing became immediately clear: the 21-year-old from Naples, Fla., had a severe stutter. Arbos, who emigrated from Cuba when he was 10, told viewers that he had few friends growing up due to his speech impediment.

But something magical happened when he began to sing. His stutter vanished and he gave a moving performance of "Bridge Over Troubled Water." As the judges unanimously put him through to Hollywood, Arbos dissolved into tears.

Equally inspiring was Mariah Pulice, a 19-year-old restaurant hostess from Darien, Ind. The last two years have been difficult for Pulice, who told judges she was recovering from anorexia. "If there was no music," she said, "I would not be alive." After singing the Beatles' "Let it Be," the judges were unanimous in their praise. "I really, really, really felt that song coming from you," said Minaj.

Carey agreed: "You touched me," she said. "I know what it's like to have to sing through tears. I'm proud of you."

But it wasn't all drama and emotion. Minaj started a baffling trend of asking handsome singers if they had a girlfriend. (She also managed to charm the shirts off of a couple of them, although you get the feeling they were happy to show their abs on national TV.) "You have a hole in your pants," she told one contestant. "Why are you looking?" he shot back.

And poor Keith Urban. Sitting between Minaj and Carey, he found himself in the crossfire. "I feel like a scratching post," he said at one point, before repeatedly banging his head on the table.

The judges found a lot of talent in Chicago. All told, 46 contestants were put through to Hollywood. The competition will head to Charlotte, N.C., next Wednesday.

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Will Obama's order lead to surge in gun research?

MILWAUKEE (AP) — Nearly as many Americans die from guns as from car crashes each year. We know plenty about the second problem and far less about the first. A scarcity of research on how to prevent gun violence has left policymakers shooting in the dark as they craft gun control measures without much evidence of what works.

That could change with President Barack Obama's order Wednesday to ease research restrictions pushed through long ago by the gun lobby. The White House declared that a 1996 law banning use of money to "advocate or promote gun control" should not keep the Centers for Disease Control and Prevention and other federal agencies from doing any work on the topic.

Obama can only do so much, though. Several experts say Congress will have to be on board before anything much changes, especially when it comes to spending money.

How severely have the restrictions affected the CDC?

Its website's A-to-Z list of health topics, which includes such obscure ones as Rift Valley fever, does not include guns or firearms. Searching the site for "guns" brings up dozens of reports on nail gun and BB gun injuries.

The restrictions have done damage "without a doubt" and the CDC has been "overly cautious" about interpreting them, said Daniel Webster, director of the Center for Gun Policy and Research at the Johns Hopkins Bloomberg School of Public Health.

"The law is so vague it puts a virtual freeze on gun violence research," said a statement from Michael Halpern of the Union of Concerned Scientists. "It's like censorship: When people don't know what's prohibited, they assume everything is prohibited."

Many have called for a public health approach to gun violence like the highway safety measures, product changes and driving laws that slashed deaths from car crashes decades ago even as the number of vehicles on the road rose.

"The answer wasn't taking away cars," said Dr. Georges Benjamin, executive director of the American Public Health Association.

However, while much is known about vehicles and victims in crashes, similar details are lacking about gun violence.

Some unknowns:

—How many people own firearms in various cities and what types.

—What states have the highest proportion of gun ownership.

—Whether gun ownership correlates with homicide rates in a city.

—How many guns used in homicides were bought legally.

—Where juveniles involved in gun fatalities got their weapons.

—What factors contribute to mass shootings like the Newtown, Conn., one that killed 26 people at a school.

"If an airplane crashed today with 20 children and 6 adults there would be a full-scale investigation of the causes and it would be linked to previous research," said Dr. Stephen Hargarten, director of the Injury Research Center at the Medical College of Wisconsin.

"There's no such system that's comparable to that" for gun violence, he said.

One reason is changes pushed by the National Rifle Association and its allies in 1996, a few years after a major study showed that people who lived in homes with firearms were more likely to be homicide or suicide victims. A rule tacked onto appropriations for the Department of Health and Human Services barred use of funds for "the advocacy or promotion of gun control."

Also, at the gun group's urging, U.S. Rep. Jay Dickey, a Republican from Arkansas, led an effort to remove $2.6 million from the CDC's injury prevention center, which had led most of the research on guns. The money was later restored but earmarked for brain injury research.

"What the NRA did was basically terrorize the research community and terrorize the CDC," said Dr. Mark Rosenberg, who headed the CDC's injury center at the time. "They went after the researchers, they went after institutions, they went after CDC in a very big way, and they went after me," he said. "They didn't want the data to be collected because they were threatened by what the data were showing."

Dickey, who is now retired, said Wednesday that his real concern was the researcher who led that gun ownership study, who Dickey described as being "in his own kingdom or fiefdom" and believing guns are bad.

He and Rosenberg said they have modified their views over time and now both agree that research is needed. They put out a joint statement Wednesday urging research that prevents firearm injuries while also protecting the rights "of legitimate gun owners."

"We ought to research the whole environment, both sides — what the benefits of having guns are and what are the benefits of not having guns," Dickey said. "We should study any part of this problem," including whether armed guards at schools would help, as the National Rifle Association has suggested.

Association officials did not respond to requests for comment. A statement Wednesday said the group "has led efforts to promote safety and responsible gun ownership" and that "attacking firearms" is not the answer. It said nothing about research.

The 1996 law "had a chilling effect. It basically brought the field of firearm-related research to a screeching halt," said Benjamin of the Public Health Association.

Webster said researchers like him had to "partition" themselves so whatever small money they received from the CDC was not used for anything that could be construed as gun policy. One example was a grant he received to evaluate a community-based program to reduce street gun violence in Baltimore, modeled after a successful program in Chicago called CeaseFire. He had to make sure the work included nothing that could be interpreted as gun control research, even though other privately funded research might.

Private funds from foundations have come nowhere near to filling the gap from lack of federal funding, Hargarten said. He and more than 100 other doctors and scientists recently sent Vice President Joe Biden a letter urging more research, saying the lack of it was compounding "the tragedy of gun violence."

Since 1973, the government has awarded 89 grants to study rabies, of which there were 65 cases; 212 grants for cholera, with 400 cases, yet only three grants for firearm injuries that topped 3 million, they wrote. The CDC spends just about $100,000 a year out of its multibillion-dollar budget on firearm-related research, New York Mayor Michael Bloomberg has said.

"It's so out of proportion to the burden, however you measure it," said Dr. Matthew Miller, associate professor of health policy at the Harvard School of Public Health. As a result, "we don't know really simple things," such as whether tighter gun rules in New York will curb gun trafficking "or is some other pipeline going to open up" in another state, he said.

What now?

CDC officials refused to discuss the topic on the record — a possible sign of how gun shy of the issue the agency has been even after the president's order.

Health and Human Services Secretary Kathleen Sebelius said in a statement that her agency is "committed to re-engaging gun violence research."

Others are more cautious. The Union of Concerned Scientists said the White House's view that the law does not ban gun research is helpful, but not enough to clarify the situation for scientists, and that congressional action is needed.

Dickey, the former congressman, agreed.

"Congress is supposed to do that. He's not supposed to do that," Dickey said of Obama's order. "The restrictions were placed there by Congress.

"What I was hoping for ... is 'let's do this together,'" Dickey said.

___

Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP

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